MetaQC: objective quality control and inclusion/exclusion criteria for genomic meta-analysis
نویسندگان
چکیده
منابع مشابه
MetaQC: objective quality control and inclusion/exclusion criteria for genomic meta-analysis
Genomic meta-analysis to combine relevant and homogeneous studies has been widely applied, but the quality control (QC) and objective inclusion/exclusion criteria have been largely overlooked. Currently, the inclusion/exclusion criteria mostly depend on ad-hoc expert opinion or naïve threshold by sample size or platform. There are pressing needs to develop a systematic QC methodology as the dec...
متن کاملStandardized Objective Performance Criteria and Control Datasets
In previous issues of Endovascular Today, we have described some ongoing initiatives in the Peripheral Vascular Devices Branch intended to optimize our regulation of peripheral vascular devices. Several of these initiatives involve the establishment of standardized objective performance criteria (OPC) and control datasets for various peripheral devices, including iliac stents and endovascular g...
متن کاملEvaluation of quality-control criteria for microarray gene expression analysis.
BACKGROUND Development of quality-control criteria to ensure reproducibility of microarray results for potential clinical application is still in its infancy. METHODS In the present studies we developed quality-control criteria and evaluated their effect in microarray data analysis using total RNA from cell lines, frozen tumors, and a commercially available reference RNA. Quality-control crit...
متن کاملAn R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detection
SUMMARY With the rapid advances and prevalence of high-throughput genomic technologies, integrating information of multiple relevant genomic studies has brought new challenges. Microarray meta-analysis has become a frequently used tool in biomedical research. Little effort, however, has been made to develop a systematic pipeline and user-friendly software. In this article, we present MetaOmics,...
متن کاملMeta-analysis of psychological intervention for chronic pain: Challenges and Strategies for research quality improvement
Aims and background: Chronic pain is a pervasive, destructive and expensive problem with a biopsychosocial nature. Psychological interventions suggested to be an effective choice for chronic pain, and many trials confirmed its effectiveness and several meta-analyses have estimated the amount of its effect. Considering the psychological and social aspects of pain, it’s possible that the Irania...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2011
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkr1071